SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c17a2016a2f47feecef132401d0e1bbbb09e25279a8a590864106740fefc1c4' 
  AND token = 'nqy3Zs1nv2sI6zzE7WX6R0AStkKcEqHZShHQDixe77U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}