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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b527c032c3fc3eceff6a76b3a02fa960a1e2c29b09354ad763a05451dc11f20' 
  AND token = 'VX5rmU7YOlFycq7dB4pPqDSxLKITzvMFB4niU3u3kHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}