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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c08bf0d865a4c68f685ed7326016aa85e06b002fd30d9dca5fcfba5f463f9eb' 
  AND token = 'KpEgIAKiSC08DfSjrVdTDimyfrxQsFJmg5Suc4Mzj5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}