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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '969e619226c72425b73eb8cd727a7d9bef550d13d26868a4f3bf61b1aeea525c' 
  AND token = 'FW0k9zL0M3n27/hj5u3w081KjMshvddyMVbXbMoW20M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}