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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c56648bbd699161eabe7e5c56130e0b2dd9b6ff8f4e52e39c22e9978f701cfc' 
  AND token = 'u6inmH8e9ny2S0M6FH7582lZklLENUHIeVPPwteYpyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}