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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4469758666f7733ea8aacf679ecec56411e9ee1b85c8eb2953794f442f6b444' 
  AND token = 'HvdUKhmrUhV18uwYQXe1NoJ5TAp+fnuqmfR3Uv55v/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}