SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9747ec523271a6d7033feaebce3b286e893d835a42562010078007ec23688f25' 
  AND token = 'AChtbZzpHHsr8/bNUhF11a1dPeTCel6MVwYUksr7vP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}