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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee5f652c54ddf9882efb80f4093e30558db4a60b599c1a5a364c10de98b5f4d' 
  AND token = '8ZmLsdowVdGHQxw2ax4eeMc/xj9YvdOSNshdZqNVXls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}