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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a447ae23f8b3e49478f8c961f18802906b9386305d048d2667e1fc17d88e2f9f' 
  AND token = '46Jo0T+P4NBGfOVKrCdR0CKVe4dcD6SEdZyRZ823A50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}