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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ea8f353f5bea03296a39a5ea705a1daaee368b89916f1119d1c6d5c075f8d0' 
  AND token = 'SIvI1iGaQK+WVIqd4UJvk7nBpsKPT/lJ5l2mDsThJQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}