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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7d898e8336e34c11f079519c036d830471003d3f0d4f3a7bdf73cff856369f' 
  AND token = 'FJ2JgT1QjA+cmHslsS7gFW/oF4vFg2YmzmxCEWaiO7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}