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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '707fbf53138686426eb569a115e9daa9a2356d997bc1ca861e3af0a4ac6053e5' 
  AND token = 'xuoVl2w/6iK3OMN8R46bBO/N0PNzzxzRp7U9wYVxSNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}