SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc33d5367561a38d20e669454d9dabcb88f88faee0498f94f63410a534751bc8' 
  AND token = 'yDhxWtAOQMp+rflNWk5wyE1naMC20TMI+SOA7A8ka8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}