SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66191044f8cc38bfbcdb182ef32d0f8f4c4fb522e4d3140ddccc5015dedb6069' 
  AND token = 'goDHq0JuFYQa0C0oJK0YYFZnwwCRp7nFdocAJRnYRag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}