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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65943938bf93a98131558f9e711e3eb2634d43018bea06cb59408971b9ed384' 
  AND token = 'pEIrAWTR16RS/pRCkcwxVwH6dmQEA52pUEzQ+Xlh12Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}