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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e8c40e5529d630ef71db02150b1dd83b67fa1f48b542a3ecd0a80da83e9b6e' 
  AND token = 'OarYjrahc6KF6aV11D/Gz0GaWFsQfxHM0qtM3ngdVyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}