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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4822cbdaa9f8362c993f8b5b1c983e39a4950249f468d97b651ef9c2400535e' 
  AND token = 'Q3Axoyjyfs5RtEcBEDNJ1wgdzHlwm7SMfeIhNX3ZXcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}