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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '348e84d34dcc1610500a0db1a3e9441e885df00e8048c6c88c8b60fec7894ad0' 
  AND token = 'EL/wh8r59bTGroDKMBdhxsbvRTP/HwwAF7O2j8YzQ78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}