SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88edb97b60fb4025fe2fb66e46654a3890fb5ef31cc4deae115b8d245e25aad3' 
  AND token = '6J7tN9vE6EFtV2lXnGHz9aPWuuYj07C8I0HykHkSzXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}