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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cccb54494f3d933cb4cc33c019e22b7042fac76504a1bcbb81f731037cd91397' 
  AND token = '/vL+XVHuIewLrH66sgqiKKHONBeX90WPNikPut+36iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}