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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d85cf35d6a4d02a228cdf811561d244e9356c619da7039d8abcd8389b2fb43' 
  AND token = 'XJfXAu7yD1yg4qscm2Yu2aidyNKvrN57eLRuqh+uzlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}