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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a13908362940f2dd7d0df07f3fe20921b5241f6ea5af6b3b0d8255e157a4506' 
  AND token = 'XKvjjTaS7ZmWSRUCzLJwVLA4F1yyp3yCETP86ilaPTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}