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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f5e03a80217c336d02c2d0f4ddbb5aefe0426361b4dd188dcd7bfbee010c0b5' 
  AND token = 'J8qu8vK+iB91yev/fE/jfi9P1rbelO8UbGjfwpTBwqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}