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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21276366d255fc89ee8d0fa01956d116be793451f6512cf7654dca34a645c6ae' 
  AND token = '2eM3hvLGHqVxYN7BVHZrhHhNhClU1Mn+eT7Ru0df/8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}