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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f10362a45ddcb09854f1302c793b9d63500d1d425ad6a67c132405243846887' 
  AND token = '4Cxg95c9Mi8cTwRYtSKUkUk5jczmXnE6LSixbDmGAjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}