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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129a578edee1e0014b9a8351583a319fa0def78f6fe866fee8bd449310841935' 
  AND token = 'yLQ9AJ0x687WZaKZVNjK9DqfhVCoIXBrhdNcNx26FT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}