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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0226ff6326c9b519c33234dc66b913cf65002fc65bfdd7ec8ab074ffa4d1227' 
  AND token = 'K+e/XvvqenOsRDHTs91fl0q3upKKQ5Oyqz0SAKBmPJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}