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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d3df8456207cb94ed04ed3562bd2c4018c3965bd09087d7f950d88c93277a35' 
  AND token = '2LLnw2OCfyKEhNunWd8i5tLK50zw+BopxOaBEAT+IkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}