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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dae2925ca505fe608df87614e43250741f44951b8489bee1bf51df2db03c80da' 
  AND token = 'iwK0U0QRNFQCn4EU24y+yDV/TRWdYe2N0Q0j+0VFz3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}