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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a41adda7d4f3afa86e0f04f089aef83f7f5eb6a6352e8a026f82a432555ecc2' 
  AND token = 'pN3/VW1C4i10wqWddPhve3YNVmkx1zyqalOcgnYtwB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}