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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ede5cd8b053596d700d3c9d8c76666e29e50845b0f6152cf857b9f20be3298c' 
  AND token = 'SbHIybzRf4RFuyLvSolMc1tIhfqg+D2qzACMoas2HwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}