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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3826df6327a8c24c19397685c2cd8426249665fff643acfa4c1cadee29491334' 
  AND token = 'M7ck1ibK6Skf7nmA46iSDvm1bupzCTll/BoU5f5bYvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}