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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6d32ce87e752eb45311d88c9ed39b04305175bb594f7e79d5d6bbbcb89912a' 
  AND token = 'iT+DBnf2Tszf9isUGjQQkl3kuW0FRSF2T7Q3IrvH9B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}