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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4cffebf89ddfc0fc085b6b4e543f811760d8a4fa8f87c7954a1c469da28ddf1' 
  AND token = 'Qd7ynNV/j/t83dlKZ5zXYrObz1CXIstlYsd2WbVtB9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}