SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26da279318537045e4728e3808357c3d9169d8e451411ce79d2ea06f62cd6188' 
  AND token = 'z3tjsVo/0nmvZvHhE852UUmyC5FxIOSSwe1y+zp3k5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}