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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc0d4cabb5bcfecc5a019cac3590952151e296e04c4618e6996f975dc85c2837' 
  AND token = '9CXb/RX/uz/nCPs8x2GAdXDY+1zdYwMAOOccQ66jZGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}