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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33783eda4c1c02a5198c9d9ef5c4217e2d2b1b8a95be6a53bffe91e6943c7d32' 
  AND token = 'adSaMFHYhb6MB7OT3a+adnBZOQ//H5nrmrFS0PwUHHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}