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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e53f46e2342bd0f01097d53c949082e62e2df63786aefe5534a2feb7dd52613' 
  AND token = '63KiL7sPJmCT7ebOSw4Qa1TQYtjtChosfwjb+uwy468=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}