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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a387d0536c8b2df8f1a5f2c3fc013637e4a7b039888092c7296a1745eef0288f' 
  AND token = 'HbcEdeLsRs75ID5JuJZYgpG2dpEbYM3KGorzNse0naM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}