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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9d87b2b4c0ebcbb9152e8b64c2971e0a082f1225db06389275a54402edc4819' 
  AND token = 'YZhfBd49aTlOFKqFtMp5fYZU2lF9zWxaWRwSZG+n/fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}