SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '738af628757456b8b54c6a0432af10446a05ad3ad8d22e79d1e3cca8f4192caa' 
  AND token = '6sZPXYhav7xvSKa8DQwrFVWLrlFzoF0e4X2MIgx4nQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}