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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80902adffffe10e5717b36f181cd3ab81c8193a273fa5202b98e3688b2b2b1d3' 
  AND token = 'AAPb9YfrWsf0xB53fIP+CKs7g5tZDKCTNoA6Y2Tugr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}