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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca01d291f44030c05d60426d9d35df3c7e53fc65ed958afe90171e7f6e58a368' 
  AND token = 'sDqNi1NT/Jm0izLeyFe7RSYl6WwzFRFSnGzEbRzZIaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}