SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54c657cdeb1dfe37b423e4016f2fb2929447e1ac5d9864d7c0ce4035106d5fa4' 
  AND token = '/3kgCkUNzbau7aWIdgoMMVN0qjeUA0OkBfenpBqbZaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}