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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5bce328049f18e9dbc17ecff5bc9977122a10da75de146c185e7cfab1c4c54e' 
  AND token = 'yD80xGmjpbC5L+Zbjl62qzviSmnVrS0zFD/iMta+Trk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}