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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0616f68ad6063ea33dbbc3cf7d7644b38c77b0795ab8d013b1b466fb3b783f14' 
  AND token = 'VWcAdT7Fo7R01ilPEK7KMJ5gBLnBBBzqcMpWw+nBtKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}