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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4f4114ee8e5c304f6a646a6aa08f45626ba8f6cc7ed2412adb54ed423181d19' 
  AND token = 'ehW8ETzVLmi7uBCp/LR1CwowUUAKPhoF2S0S1NVBwpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}