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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd48ae153d7fb0b40d8a7794009b7eeb691e0be1ef5bc53e8f7a1f6005c0c978' 
  AND token = 'rlW+R7Y5YGP3WZYXYGpX6fm0gY1QfkcIHHL+da/KfAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}