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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c26d0820069b8d672eee5b26571f615ddbb9865b53352652c8da2e7c312a5e6' 
  AND token = 'RJNoKBT8UvbQkPviwRZq2bdWykcZTnCr5NpuQokXlz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}