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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea5b00e64691e32fbe23f1762505ea06b48118496e5466bb2db75d42eea2e176' 
  AND token = 'nupie0Hx5UHJhBVWIVO/p1tOX4lQanFhHzG0RzlNZDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}